The residents armed with machetes, clubs and other dangerous implements, besieged the premises of the Bakaano Police Station in protest, vandalising about 15 vehicles belonging to private individuals.
The injured are currently receiving treatment at the Cape Coast Metropolitan Hospital.
An eye witness, who spoke on condition of anonymity, told the Ghana News Agency (GNA) that the irate residents went to the Police station with gallons of fuel and attempted to set the place ablaze but they were stopped by the Police.
They later went to the charge office and inflicted several wounds on the officer on duty, the witness said.
The action by the residents compelled the Police to fire shots and tear gas, thus injuring three persons at the scene.
The Police reportedly continued with the operation to the Ntsin Community, firing tear gas and warning shots in search of the culprits identified in the clash at the Police Station.
Meanwhile, five persons have so far been arrested and are assisting the Police in an investigation.
The Central Regional Command, two days ago, at press conference, dismissed reports that the deceased had been shot by the Police and insisted that the operation was conducted in the highest professional manner as possible to strengthen security in the area.
The Regional Police Commander, Deputy Commissioner of Police (DCOP) Ransford Moses Ninson, explained that the deceased who was detained in the Bakaano Police cells fell sick and was rushed to the hospital for treatment but died on admission.