Ghana will be missing three key players when they play Niger in their decisive Group B clash at the 2013 Africa Cup of Nations on Monday.
Influential midfielder Mubarak Wakaso, experienced enforcer Anthony Annan and striker Richmond Boakye Yiadom are all not available for the match in Port Elizabeth.
The trio missed the Black Stars final training session at Nelson Mandela Metropolitan University on Sunday night.
Spain-based Wakaso misses the game as he is serving a one-match ban after picking up his second booking of the tournament for his goal celebration against Mali.
The Espanyol would have missed the match against Niger even if he was not suspended because he is nursing a knee injury he suffered in the match against Mali.
Ghana coach Kwesi Appiah has disclosed that he should be fit for the quarter-finals, assuming the Black Stars qualify.
The Black Stars will still be missing Italy-based striker Richmond Boakye-Yiadom, who has not fully recovered from a groin injury sustained during their training camp in Abu Dhabi.
Annan also remains on the sidelines after aggravating an ankle injury during Ghana?s opening Group B match against DR Congo.
A draw will be enough to take Ghana into the quarter-finals of the Africa Cup of Nations while a win ensures they top Group B.
Niger could still qualify if they win, however if they do and Mali draw with DR Congo then it would come down to a mini-table within the table.