Medeama returned to the summit of the league table after an 87th minute winner from second-half substitute, Kabiru Imoro ensured that Medeama beat Heart of Lions 1-0 at the Tarkwa T&A Park.
Aduana dropped to second place after they drew 1-1 with Berekum Arsenals at the Berekum Golden City Park.
Asante Kotoko maintained their unbeaten run after 10 league games when they held free scoring Ebusua Dwarfs to a goalless at the Robert Mensah Stadium at Cape Coast.
David Duncan suffered his defeat as Hearts of Oak Coach when Ashantigold broke a 17-year winless streak in Accra to beat Hearts 1-0 at the Accra Sports Stadium.
In the Tema derby, in-form Kotoko loanee, Yahaya Mohammed was on hand again for Amidaus to deny Tema Youth a derby win.
An 81st minute strike from second-half substitute, Ebenezer Ofori was enough to secure all three points for New Edubiase against Liberty at the Bekwai Gyamfi Park.
Wa All Stars deepened RTU?s woes with a hat-trick from Seidu Salifu winning the match for them at home.
The match between King Faisal and Berekum Chelsea has been rescheduled for Monday after it was rained-off on Sunday.
SCORES AT GLANCE
FT: Ebusua Dwarfs 0-0 Kotoko
FT: Hearts 0-1 Ashantigold
FT: Tema Youth 1-1 Amidaus Professionals
FT: New Edubiase 1-0 Liberty Professionals
FT: All Stars 3-0 Real Tamale United
FT: Medeama 1-0 Heart of Lions
FT: Berekum Arsenals 1-1 Aduana Stars
**: King Faisal 1-1 Berekum Chelsea
** Rained off