He was born in Swalaba, Accra and brought up in Ga Maamli (Accra Central) and in the Nima area of Accra.
His father’s residence, Betty House, at Korle Wokon in Accra, was effectively the headquarters of the country’s first political party, the United Gold Coast Convention (UGCC), after it was formed at Saltpond on 4 August 1947.
Three of the ‘Big Six’ who were his relatives were all founding fathers of Ghana J. B. Danquah (grand uncle), William Ofori Atta (uncle) and Edward Akufo-Addo (the third Chief Justice of Ghana and later ceremonial President of the Republic from 1969 to 1972), who was his father.
Nana Addo received his primary education at the Government Boys School and went to O’Reilly Secondary School, and later at the Rowe Road School (now Kinbu), both in Accra Central. He went to England to study for his O Level and A Level examinations at Lancing College, Sussex.
He returned to Ghana in 1962 to teach at Accra Academy before going to read Economics at the University of Ghana, Legon, in 1964, earning a BSc (Econ) degree in 1967. He subsequently studied law in the UK and was called to the English Bar (Middle Temple) in July 1971. Akufo-Addo was called to the Ghana Bar in July 1975 along with notable Ghanaian politicians such as Nana Ato Dadzie and Tsatsu Tsikata.
Nana Akufo-Addo first run for president in 2008 as flagbearer of the NPP but lost to the late Prof John Evans Atta Mills.
He went again in another attempt in 2012 but failed again when John Mahama swept the victory away.
Indeed, the coming November 2016 elections will no doubt be his third attempt to ascend the throne of the Presidency in Ghana.